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Empagliflozin prevents neointima formation by impairing smooth muscle cell proliferation and accelerating endothelial regeneration

BACKGROUND: Empagliflozin, an inhibitor of the sodium glucose co-transporter 2 (SGLT2) and developed as an anti-diabetic agent exerts additional beneficial effects on heart failure outcomes. However, the effect of empagliflozin on vascular cell function and vascular remodeling processes remains larg...

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Detalles Bibliográficos
Autores principales: Dutzmann, Jochen, Bode, Lena Marie, Kalies, Katrin, Korte, Laura, Knöpp, Kai, Kloss, Frederik Julius, Sirisko, Mirja, Pilowski, Claudia, Koch, Susanne, Schenk, Heiko, Daniel, Jan-Marcus, Bauersachs, Johann, Sedding, Daniel G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9396257/
https://www.ncbi.nlm.nih.gov/pubmed/36017090
http://dx.doi.org/10.3389/fcvm.2022.956041