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Empagliflozin prevents neointima formation by impairing smooth muscle cell proliferation and accelerating endothelial regeneration
BACKGROUND: Empagliflozin, an inhibitor of the sodium glucose co-transporter 2 (SGLT2) and developed as an anti-diabetic agent exerts additional beneficial effects on heart failure outcomes. However, the effect of empagliflozin on vascular cell function and vascular remodeling processes remains larg...
Autores principales: | Dutzmann, Jochen, Bode, Lena Marie, Kalies, Katrin, Korte, Laura, Knöpp, Kai, Kloss, Frederik Julius, Sirisko, Mirja, Pilowski, Claudia, Koch, Susanne, Schenk, Heiko, Daniel, Jan-Marcus, Bauersachs, Johann, Sedding, Daniel G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9396257/ https://www.ncbi.nlm.nih.gov/pubmed/36017090 http://dx.doi.org/10.3389/fcvm.2022.956041 |
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