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Extracellular Polysaccharide from Rhizopus nigricans Inhibits Hepatocellular Carcinoma via miR-494-3p/TRIM36 Axis and Cyclin E Ubiquitination

BACKGROUND AND AIMS: This study was designed to uncover the mechanism for extracellular polysaccharide (EPS1-1)-mediated effects on hepatocellular carcinoma (HCC) development. METHODS: HCC cells were treated with EPS1-1, miR-494-3p mimic, sh-TRIM36, and pcDNA3.1-TRIM36. The levels of miR-494-3p and...

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Detalles Bibliográficos
Autores principales: Yan, Haixiong, Ma, XiaoQian, Mi, Ze, He, Zhenhu, Rong, Pengfei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: XIA & HE Publishing Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9396321/
https://www.ncbi.nlm.nih.gov/pubmed/36062277
http://dx.doi.org/10.14218/JCTH.2021.00301