Cargando…

Overexpression of Hepcidin Alleviates Steatohepatitis and Fibrosis in a Diet-induced Nonalcoholic Steatohepatitis

BACKGROUND AND AIMS: Iron overload can contribute to the progression of nonalcoholic fatty liver disease (NAFLD) to nonalcoholic steatohepatitis (NASH). Hepcidin (Hamp), which is primarily synthesized in hepatocytes, is a key regulator of iron metabolism. However, the role of Hamp in NASH remains un...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Hui, Zhao, Wenshan, Yan, Xuzhen, Huang, Tao, Yang, Aiting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: XIA & HE Publishing Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9396326/
https://www.ncbi.nlm.nih.gov/pubmed/36062292
http://dx.doi.org/10.14218/JCTH.2021.00289