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Overexpression of Hepcidin Alleviates Steatohepatitis and Fibrosis in a Diet-induced Nonalcoholic Steatohepatitis
BACKGROUND AND AIMS: Iron overload can contribute to the progression of nonalcoholic fatty liver disease (NAFLD) to nonalcoholic steatohepatitis (NASH). Hepcidin (Hamp), which is primarily synthesized in hepatocytes, is a key regulator of iron metabolism. However, the role of Hamp in NASH remains un...
Autores principales: | Chen, Hui, Zhao, Wenshan, Yan, Xuzhen, Huang, Tao, Yang, Aiting |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
XIA & HE Publishing Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9396326/ https://www.ncbi.nlm.nih.gov/pubmed/36062292 http://dx.doi.org/10.14218/JCTH.2021.00289 |
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