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Transplantation of Mesenchymal Stem Cells Attenuates Acute Liver Failure in Mice via an Interleukin-4-dependent Switch to the M2 Macrophage Anti-inflammatory Phenotype

BACKGROUND AND AIMS: Transplantation of mesenchymal stem cells (MSCs) derived from bone marrow (BM) is an alternative treatment of acute liver failure (ALF) mainly because of the resulting anti-inflammatory activity. It is not known how MSCs regulate local immune responses and liver regeneration. Th...

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Detalles Bibliográficos
Autores principales: Wang, Jinglin, Ding, Haoran, Zhou, Jingchao, Xia, Senzhe, Shi, Xiaolei, Ren, Haozhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: XIA & HE Publishing Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9396329/
https://www.ncbi.nlm.nih.gov/pubmed/36062289
http://dx.doi.org/10.14218/JCTH.2021.00127