TNF-α inhibitor ameliorates immune-related arthritis and pneumonitis in humanized mice

OBJECTIVES: This study aimed at establishing a mouse model of immune-related adverse in humanized BALB/c-hPD1/hCTLA4 mice to investigate their potential pathogenesis and explore therapeutic targets for immune-related arthritis and pneumonitis. METHODS: Humanized BALB/c-hPD1/hCTLA4 mice were injected...

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Detalles Bibliográficos
Autores principales: Gao, Jian, Miao, Jinlin, Sun, Haoyang, Fu, Xianghui, Zhang, Peiyan, Chen, Zhinan, Zhu, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9396351/
https://www.ncbi.nlm.nih.gov/pubmed/36016934
http://dx.doi.org/10.3389/fimmu.2022.955812

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9396351/
https://www.ncbi.nlm.nih.gov/pubmed/36016934
http://dx.doi.org/10.3389/fimmu.2022.955812

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