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TNF-α inhibitor ameliorates immune-related arthritis and pneumonitis in humanized mice

OBJECTIVES: This study aimed at establishing a mouse model of immune-related adverse in humanized BALB/c-hPD1/hCTLA4 mice to investigate their potential pathogenesis and explore therapeutic targets for immune-related arthritis and pneumonitis. METHODS: Humanized BALB/c-hPD1/hCTLA4 mice were injected...

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Detalles Bibliográficos
Autores principales:	Gao, Jian, Miao, Jinlin, Sun, Haoyang, Fu, Xianghui, Zhang, Peiyan, Chen, Zhinan, Zhu, Ping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9396351/ https://www.ncbi.nlm.nih.gov/pubmed/36016934 http://dx.doi.org/10.3389/fimmu.2022.955812

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