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Using a comprehensive approach to investigate the interaction between Kinesin-5/Eg5 and the microtubule

Kinesins are microtubule-based motor proteins that play important roles ranging from intracellular transport to cell division. Human Kinesin-5 (Eg5) is essential for mitotic spindle assembly during cell division. By combining molecular dynamics (MD) simulations with other multi-scale computational a...

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Detalles Bibliográficos
Autores principales: Guo, Wenhan, Sun, Shengjie, Sanchez, Jason E., Lopez-Hernandez, Alan E., Ale, Tolulope A., Chen, Jiawei, Afrin, Tanjina, Qiu, Weihong, Xie, Yixin, Li, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9396395/
https://www.ncbi.nlm.nih.gov/pubmed/36051882
http://dx.doi.org/10.1016/j.csbj.2022.08.020