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Molecular and functional interactions of alpha-synuclein with Rab3a

Alpha-synuclein (a-Syn) is a presynaptic protein, the misfolding of which is associated with Parkinson’s disease. Rab GTPases are small guanine nucleotide binding proteins that play key roles in vesicle trafficking and have been associated with a-Syn function and dysfunction. a-Syn is enriched on sy...

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Detalles Bibliográficos
Autores principales: Lv, Guohua, Ko, Myung Soo, Das, Tapojyoti, Eliezer, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9396396/
https://www.ncbi.nlm.nih.gov/pubmed/35809645
http://dx.doi.org/10.1016/j.jbc.2022.102239