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Evaluating how clear the questions being investigated in randomised trials are: systematic review of estimands

OBJECTIVES: To evaluate how often the precise research question being addressed about an intervention (the estimand) is stated or can be determined from reported methods, and to identify what types of questions are being investigated in phase 2-4 randomised trials. DESIGN: Systematic review of the c...

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Detalles Bibliográficos
Autores principales: Cro, Suzie, Kahan, Brennan C, Rehal, Sunita, Chis Ster, Anca, Carpenter, James R, White, Ian R, Cornelius, Victoria R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group Ltd. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9396446/
https://www.ncbi.nlm.nih.gov/pubmed/35998928
http://dx.doi.org/10.1136/bmj-2022-070146