Frataxin controls ketone body metabolism through regulation of OXCT1

Friedreich’s ataxia (FRDA) is an autosomal recessive neurodegenerative disease caused by the deficiency of mitochondrial protein frataxin, which plays a crucial role in iron–sulphur cluster formation and ATP production. The cellular function of frataxin is not entirely known. Here, we demonstrate th...

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Detalles Bibliográficos
Autores principales: Dong, Yi NA, Mesaros, Clementina, Xu, Peining, Mercado-Ayón, Elizabeth, Halawani, Sarah, Ngaba, Lucie Vanessa, Warren, Nathan, Sleiman, Patrick, Rodden, Layne N, Schadt, Kimberly A, Blair, Ian A, Lynch, David R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Biological, Health, and Medical Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9396447/
https://www.ncbi.nlm.nih.gov/pubmed/36016708
http://dx.doi.org/10.1093/pnasnexus/pgac142

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9396447/
https://www.ncbi.nlm.nih.gov/pubmed/36016708
http://dx.doi.org/10.1093/pnasnexus/pgac142

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