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Knockout of Sirt2 alleviates traumatic brain injury in mice

Sirtuin 2 (SIRT2) inhibition or Sirt2 knockout in animal models protects against the development of neurodegenerative diseases and cerebral ischemia. However, the role of SIRT2 in traumatic brain injury (TBI) remains unclear. In this study, we found that knockout of Sirt2 in a mouse model of TBI red...

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Detalles Bibliográficos
Autores principales: Wang, Wei, Gong, Qiu-Yuan, Cai, Lin, Jing, Yao, Yang, Dian-Xu, Yuan, Fang, Chen, Hao, Tian, Heng-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9396492/
https://www.ncbi.nlm.nih.gov/pubmed/35900429
http://dx.doi.org/10.4103/1673-5374.346457