The Alzheimer’s disease-associated gene TREML2 modulates inflammation by regulating microglia polarization and NLRP3 inflammasome activation

Triggering receptor expressed on myeloid cells-like 2 (TREML2) is a newly identified susceptibility gene for Alzheimer’s disease (AD). It encodes a microglial inflammation-associated receptor. To date, the potential role of microglial TREML2 in neuroinflammation in the context of AD remains unclear....

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Detalles Bibliográficos
Autores principales: Wang, Si-Yu, Fu, Xin-Xin, Duan, Rui, Wei, Bin, Cao, Hai-Ming, Yan, E, Chen, Shuai-Yu, Zhang, Ying-Dong, Jiang, Teng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9396521/
https://www.ncbi.nlm.nih.gov/pubmed/35900442
http://dx.doi.org/10.4103/1673-5374.346468

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9396521/
https://www.ncbi.nlm.nih.gov/pubmed/35900442
http://dx.doi.org/10.4103/1673-5374.346468

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