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The human blood transcriptome exhibits time-of-day-dependent response to hypoxia: Lessons from the highest city in the world

High altitude exposes humans to hypobaric hypoxia, which induces various physiological and molecular changes. Recent studies point toward interaction between circadian rhythms and the hypoxic response, yet their human relevance is lacking. Here, we examine the effect of different high altitudes in c...

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Detalles Bibliográficos
Autores principales: Manella, Gal, Ezagouri, Saar, Champigneulle, Benoit, Gaucher, Jonathan, Mendelson, Monique, Lemarie, Emeline, Stauffer, Emeric, Pichon, Aurélien, Howe, Connor A., Doutreleau, Stéphane, Golik, Marina, Verges, Samuel, Asher, Gad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9396531/
https://www.ncbi.nlm.nih.gov/pubmed/35977481
http://dx.doi.org/10.1016/j.celrep.2022.111213