Cargando…

Subtype-Selective Positive Modulation of K(Ca)2.3 Channels Increases Cilia Length

[Image: see text] Small-conductance Ca(2+)-activated potassium (K(Ca)2.x) channels are gated exclusively by intracellular Ca(2+). The activation of K(Ca)2.3 channels induces hyperpolarization, which augments Ca(2+) signaling in endothelial cells. Cilia are specialized Ca(2+) signaling compartments....

Descripción completa

Detalles Bibliográficos
Autores principales: Nam, Young-Woo, Pala, Rajasekharreddy, El-Sayed, Naglaa Salem, Larin-Henriquez, Denisse, Amirrad, Farideh, Yang, Grace, Rahman, Mohammad Asikur, Orfali, Razan, Downey, Myles, Parang, Keykavous, Nauli, Surya M., Zhang, Miao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9396613/
https://www.ncbi.nlm.nih.gov/pubmed/35947779
http://dx.doi.org/10.1021/acschembio.2c00469