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Synthesis of Thiomorpholine via a Telescoped Photochemical Thiol–Ene/Cyclization Sequence in Continuous Flow

[Image: see text] A procedure for the continuous flow generation of thiomorpholine in a two-step telescoped format was developed. The key step was the photochemical thiol–ene reaction of cysteamine hydrochloride and vinyl chloride as low-cost starting materials. This reaction could be conducted unde...

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Detalles Bibliográficos
Autores principales: Steiner, Alexander, Nelson, Ryan C., Dallinger, Doris, Kappe, C. Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9396661/
https://www.ncbi.nlm.nih.gov/pubmed/36032361
http://dx.doi.org/10.1021/acs.oprd.2c00214