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Effective Combination Immunotherapy with Oncolytic Adenovirus and Anti-PD-1 for Treatment of Human and Murine Ovarian Cancers

SIMPLE SUMMARY: This study was conducted to find a new, more efficient, treatment for ovarian cancer. A combination of an oncolytic adenovirus (TILT-123) with immune checkpoint inhibitors was employed to treat ex vivo patient samples and was found statistically significantly more effective than cont...

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Detalles Bibliográficos
Autores principales: Heiniö, Camilla, Clubb, James, Kudling, Tatiana, Quixabeira, Dafne, Cervera-Carrascon, Victor, Havunen, Riikka, Grönberg-Vähä-Koskela, Susanna, Santos, João Manuel, Tapper, Johanna, Kanerva, Anna, Hemminki, Akseli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9396998/
https://www.ncbi.nlm.nih.gov/pubmed/35997357
http://dx.doi.org/10.3390/diseases10030052