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Multiple Asparaginase Infusions Cause Increasingly Severe Acute Hyperammonemia

Adverse reactions during and shortly after infusing asparaginase for the treatment of acute lymphoblastic leukemia can increase in severity with later doses, limiting further use and increasing relapse risk. Although asparaginase is associated with hyperammonemia, the magnitude of the increase in se...

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Detalles Bibliográficos
Autores principales: Buddington, Randal K, Buddington, Karyl K, Howard, Scott C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9397007/
https://www.ncbi.nlm.nih.gov/pubmed/35997335
http://dx.doi.org/10.3390/medsci10030043