On the Rapid Calculation of Binding Affinities for Antigen and Antibody Design and Affinity Maturation Simulations

The accurate and efficient calculation of protein-protein binding affinities is an essential component in antibody and antigen design and optimization, and in computer modeling of antibody affinity maturation. Such calculations remain challenging despite advances in computer hardware and algorithms,...

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Detalles Bibliográficos
Autores principales: Conti, Simone, Lau, Edmond Y., Ovchinnikov, Victor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9397028/
https://www.ncbi.nlm.nih.gov/pubmed/35997345
http://dx.doi.org/10.3390/antib11030051

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9397028/
https://www.ncbi.nlm.nih.gov/pubmed/35997345
http://dx.doi.org/10.3390/antib11030051

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