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Polyamine-Based Nanostructures Share Polyamine Transport Mechanisms with Native Polyamines and Their Analogues: Significance for Polyamine-Targeted Therapy

Polyamines are small polycationic alkylamines involved in many fundamental cellular processes, including cell proliferation, survival, and protection from oxidative stress. Polyamine homeostasis is tightly regulated through coordinated biosynthesis, catabolism, and transport. Due to their continual...

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Detalles Bibliográficos
Autores principales: Holbert, Cassandra E., Foley, Jackson R., Yu, Ao, Murray Stewart, Tracy, Phanstiel, Otto, Oupicky, David, Casero, Robert A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9397040/
https://www.ncbi.nlm.nih.gov/pubmed/35997336
http://dx.doi.org/10.3390/medsci10030044