Anticalin N- or C-Terminal on a Monoclonal Antibody Affects Both Production and In Vitro Functionality

Bispecific antibodies (BsAbs) represent an important advance in innovative therapeutic strategies. Among the countless formats of BsAbs, fusion with molecules such as anticalins linked to a monoclonal antibody (mAb), represents an easy and low-cost way to obtain innovative molecules. We fused an ant...

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Detalles Bibliográficos
Autores principales: Aubrey, Nicolas, Gouilleux-Gruart, Valérie, Dhommée, Christine, Mariot, Julie, Boursin, Fanny, Albrecht, Nicolas, Bergua, Cécile, Croix, Cécile, Gilotin, Mäelle, Haudebourg, Eloi, Horiot, Catherine, Matthias, Laetitia, Mouline, Caroline, Lajoie, Laurie, Munos, Audrey, Ferry, Gilles, Viaud-Massuard, Marie-Claude, Thibault, Gilles, Velge-Roussel, Florence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9397084/
https://www.ncbi.nlm.nih.gov/pubmed/35997348
http://dx.doi.org/10.3390/antib11030054

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9397084/
https://www.ncbi.nlm.nih.gov/pubmed/35997348
http://dx.doi.org/10.3390/antib11030054

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