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Anticalin N- or C-Terminal on a Monoclonal Antibody Affects Both Production and In Vitro Functionality
Bispecific antibodies (BsAbs) represent an important advance in innovative therapeutic strategies. Among the countless formats of BsAbs, fusion with molecules such as anticalins linked to a monoclonal antibody (mAb), represents an easy and low-cost way to obtain innovative molecules. We fused an ant...
Autores principales: | Aubrey, Nicolas, Gouilleux-Gruart, Valérie, Dhommée, Christine, Mariot, Julie, Boursin, Fanny, Albrecht, Nicolas, Bergua, Cécile, Croix, Cécile, Gilotin, Mäelle, Haudebourg, Eloi, Horiot, Catherine, Matthias, Laetitia, Mouline, Caroline, Lajoie, Laurie, Munos, Audrey, Ferry, Gilles, Viaud-Massuard, Marie-Claude, Thibault, Gilles, Velge-Roussel, Florence |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9397084/ https://www.ncbi.nlm.nih.gov/pubmed/35997348 http://dx.doi.org/10.3390/antib11030054 |
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