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Active-Site Engineering Switches Carbohydrate Regiospecificity in a Fungal Copper Radical Oxidase

[Image: see text] Copper radical oxidases (CROs) from Auxiliary Activity Family 5, Subfamily 2 (AA5_2), are organic cofactor-free biocatalysts for the selective oxidation of alcohols to the corresponding aldehydes. AA5_2 CROs comprise canonical galactose-6-oxidases as well as the more recently disco...

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Detalles Bibliográficos
Autores principales: Mathieu, Yann, Cleveland, Maria E., Brumer, Harry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9397409/
https://www.ncbi.nlm.nih.gov/pubmed/36033369
http://dx.doi.org/10.1021/acscatal.2c01956