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Active-Site Engineering Switches Carbohydrate Regiospecificity in a Fungal Copper Radical Oxidase
[Image: see text] Copper radical oxidases (CROs) from Auxiliary Activity Family 5, Subfamily 2 (AA5_2), are organic cofactor-free biocatalysts for the selective oxidation of alcohols to the corresponding aldehydes. AA5_2 CROs comprise canonical galactose-6-oxidases as well as the more recently disco...
Autores principales: | Mathieu, Yann, Cleveland, Maria E., Brumer, Harry |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9397409/ https://www.ncbi.nlm.nih.gov/pubmed/36033369 http://dx.doi.org/10.1021/acscatal.2c01956 |
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