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DCN released from ferroptotic cells ignites AGER-dependent immune responses

Ferroptosis is a form of inflammatory cell death for which key mediators remain obscure. Here, we report that the proteoglycan decorin (DCN) is released by cells that are dying from ferroptosis and then acts as an alarm signal to trigger innate and adaptive immune responses. The early release of DCN...

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Detalles Bibliográficos
Autores principales: Liu, Jiao, Zhu, Shan, Zeng, Ling, Li, Jingbo, Klionsky, Daniel J., Kroemer, Guido, Jiang, Jianxin, Tang, Daolin, Kang, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9397459/
https://www.ncbi.nlm.nih.gov/pubmed/34964698
http://dx.doi.org/10.1080/15548627.2021.2008692