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DCN released from ferroptotic cells ignites AGER-dependent immune responses
Ferroptosis is a form of inflammatory cell death for which key mediators remain obscure. Here, we report that the proteoglycan decorin (DCN) is released by cells that are dying from ferroptosis and then acts as an alarm signal to trigger innate and adaptive immune responses. The early release of DCN...
Autores principales: | Liu, Jiao, Zhu, Shan, Zeng, Ling, Li, Jingbo, Klionsky, Daniel J., Kroemer, Guido, Jiang, Jianxin, Tang, Daolin, Kang, Rui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9397459/ https://www.ncbi.nlm.nih.gov/pubmed/34964698 http://dx.doi.org/10.1080/15548627.2021.2008692 |
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