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A Computational Study on the Interaction of NSP10 and NSP14: Unraveling the RNA Synthesis Proofreading Mechanism in SARS-CoV-2, SARS-CoV, and MERS-CoV

[Image: see text] The interaction of exoribonuclease (ExoN) nonstructural protein (NSP14) with NSP10 co-factors is crucial for high-fidelity proofreading activity of coronavirus replication and transcription. Proofreading function is critical for maintaining the large genomes to ensure replication p...

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Detalles Bibliográficos
Autores principales: Sarma, Himakshi, Sastry, G. Narahari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9397572/
https://www.ncbi.nlm.nih.gov/pubmed/36035077
http://dx.doi.org/10.1021/acsomega.2c03007