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TGFβ Signaling Activated by Cancer-Associated Fibroblasts Determines the Histological Signature of Lung Adenocarcinoma

Invasive lung adenocarcinoma (LADC) can be classified histologically as lepidic, acinar, papillary, micropapillary, or solid. Most LADC tumors manifest several of these histological subtypes, with heterogeneity being related to therapeutic resistance. We report here that in immunodeficient mice, hum...

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Detalles Bibliográficos
Autores principales: Sato, Ryo, Imamura, Kosuke, Semba, Takashi, Tomita, Yusuke, Saeki, Sho, Ikeda, Koei, Komohara, Yoshihiro, Suzuki, Makoto, Sakagami, Takuro, Saya, Hideyuki, Arima, Yoshimi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9397619/
https://www.ncbi.nlm.nih.gov/pubmed/34289987
http://dx.doi.org/10.1158/0008-5472.CAN-20-3941