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A PLCB1–PI3K–AKT Signaling Axis Activates EMT to Promote Cholangiocarcinoma Progression

As a member of the phospholipase family, phospholipase C beta 1 (PLCB1) is involved in phospholipid hydrolysis and is frequently upregulated in human cancer. However, little is known about the role of PLCB1 in cholangiocarcinoma (CCA). In this study, we uncover a role for PLCB1 in CCA progression an...

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Detalles Bibliográficos
Autores principales: Liang, Shuhang, Guo, Hongrui, Ma, Kun, Li, Xianying, Wu, Dehai, Wang, Yiqi, Wang, Wei, Zhang, Shugeng, Cui, Yifeng, Liu, Yufeng, Sun, Linmao, Zhang, Bo, Xin, Mengyang, Zhang, Ning, Zhou, Huanran, Liu, Yao, Wang, Jiabei, Liu, Lianxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9397629/
https://www.ncbi.nlm.nih.gov/pubmed/34580062
http://dx.doi.org/10.1158/0008-5472.CAN-21-1538