Super Enhancer-Mediated Upregulation of HJURP Promotes Growth and Survival of t(4;14)-Positive Multiple Myeloma

Multiple myeloma is an incurable malignancy with marked clinical and genetic heterogeneity. The cytogenetic abnormality t(4;14) (p16.3;q32.3) confers aggressive behavior in multiple myeloma. Recently, essential oncogenic drivers in a wide range of cancers have been shown to be controlled by super-en...

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Detalles Bibliográficos
Autores principales: Jia, Yunlu, Zhou, Jianbiao, Tan, Tze King, Chung, Tae-Hoon, Chen, Yongxia, Chooi, Jing-Yuan, Sanda, Takaomi, Fullwood, Melissa J., Xiong, Sinan, Toh, Sabrina H.M., Balan, Kalpnaa, Wong, Regina W.J., Lim, Julia S.L., Zhang, Enfan, Cai, Zhen, Shen, Peng, Chng, Wee Joo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Molecular Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9397631/
https://www.ncbi.nlm.nih.gov/pubmed/34893510
http://dx.doi.org/10.1158/0008-5472.CAN-21-0921

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9397631/
https://www.ncbi.nlm.nih.gov/pubmed/34893510
http://dx.doi.org/10.1158/0008-5472.CAN-21-0921

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