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Novel Oncogenic Transcription Factor Cooperation in RB-Deficient Cancer

The retinoblastoma tumor suppressor (RB) is a critical regulator of E2F-dependent transcription, controlling a multitude of protumorigenic networks including but not limited to cell-cycle control. Here, genome-wide assessment of E2F1 function after RB loss in isogenic models of prostate cancer revea...

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Detalles Bibliográficos
Autores principales: Mandigo, Amy C., Shafi, Ayesha A., McCann, Jennifer J., Yuan, Wei, Laufer, Talya S., Bogdan, Denisa, Gallagher, Lewis, Dylgjeri, Emanuela, Semenova, Galina, Vasilevskaya, Irina A., Schiewer, Matthew J., McNair, Chris M., de Bono, Johann S., Knudsen, Karen E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9397633/
https://www.ncbi.nlm.nih.gov/pubmed/34625422
http://dx.doi.org/10.1158/0008-5472.CAN-21-1159