Specific Activation of the CD271 Intracellular Domain in Combination with Chemotherapy or Targeted Therapy Inhibits Melanoma Progression

CD271 (NGFR) is a neurotrophin receptor that belongs to the tumor necrosis receptor (TNFR) family. Upon ligand binding, CD271 can mediate either survival or cell death. Although the role of CD271 as a marker of tumor-initiating cells is still a matter of debate, its role in melanoma progression has...

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Detalles Bibliográficos
Autores principales: Saltari, Annalisa, Dzung, Andreas, Quadri, Marika, Tiso, Natascia, Facchinello, Nicola, Hernández-Barranco, Alberto, Garcia-Silva, Susana, Nogués, Laura, Stoffel, Corinne Isabelle, Cheng, Phil F., Turko, Patrick, Eichhoff, Ossia M., Truzzi, Francesca, Marconi, Alessandra, Pincelli, Carlo, Peinado, Héctor, Dummer, Reinhard, Levesque, Mitchell P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2021
Materias:
Translational Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9397645/
https://www.ncbi.nlm.nih.gov/pubmed/34645608
http://dx.doi.org/10.1158/0008-5472.CAN-21-0117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9397645/
https://www.ncbi.nlm.nih.gov/pubmed/34645608
http://dx.doi.org/10.1158/0008-5472.CAN-21-0117

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