The Amyloid Cascade Hypothesis 2.0: On the Possibility of Once-in-a-Lifetime-Only Treatment for Prevention of Alzheimer’s Disease and for Its Potential Cure at Symptomatic Stages

We posit that Alzheimer’s disease (AD) is driven by amyloid-β (Aβ) generated in the amyloid-β protein precursor (AβPP) independent pathway activated by AβPP-derived Aβ accumulated intraneuronally in a life-long process. This interpretation constitutes the Amyloid Cascade Hypothesis 2.0 (ACH2.0). It...

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Detalles Bibliográficos
Autores principales: Volloch, Vladimir, Rits-Volloch, Sophia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2022
Materias:
Hypothesis/Theory
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9397896/
https://www.ncbi.nlm.nih.gov/pubmed/36072366
http://dx.doi.org/10.3233/ADR-220031

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9397896/
https://www.ncbi.nlm.nih.gov/pubmed/36072366
http://dx.doi.org/10.3233/ADR-220031

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