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Alterations in Retinal Signaling Across Age and Sex in 3xTg Alzheimer’s Disease Mice

BACKGROUND: Visual disturbances often precede cognitive dysfunction in patients with Alzheimer’s disease (AD) and may coincide with early accumulation of amyloid-β (Aβ) protein in the retina. These findings have inspired critical research on in vivo ophthalmic Aβ imaging for disease biomarker detect...

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Detalles Bibliográficos
Autores principales: Frame, Gabrielle, Schuller, Adam, Smith, Matthew A., Crish, Samuel D., Dengler-Crish, Christine M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9398084/
https://www.ncbi.nlm.nih.gov/pubmed/35599482
http://dx.doi.org/10.3233/JAD-220016