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Oncogenic Activity of Glucocorticoid Receptor β Is Controlled by Ubiquitination-Dependent Interaction with USP49 in Glioblastoma Cells

Previous studies have demonstrated that glucocorticoid receptor β (GRβ) functions as an oncoprotein, regulating the malignant phenotypes and stem-like cell maintaining in human glioblastoma (GBM). Of the glucocorticoid receptor (GR) isoforms, GRβ and GRα are highly homologous, though the mechanism u...

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Detalles Bibliográficos
Autores principales: Hu, Yaling, Jiang, Yingdi, Zhang, Zhenhao, Wang, Jingjing, Zhang, Bo, Gong, Lingli, Ji, Li, Pu, Zhening, Yang, Xusheng, Zou, Jian, Yin, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9398152/
https://www.ncbi.nlm.nih.gov/pubmed/34610959
http://dx.doi.org/10.1158/1541-7786.MCR-20-1068