Cargando…
Oncogenic Activity of Glucocorticoid Receptor β Is Controlled by Ubiquitination-Dependent Interaction with USP49 in Glioblastoma Cells
Previous studies have demonstrated that glucocorticoid receptor β (GRβ) functions as an oncoprotein, regulating the malignant phenotypes and stem-like cell maintaining in human glioblastoma (GBM). Of the glucocorticoid receptor (GR) isoforms, GRβ and GRα are highly homologous, though the mechanism u...
Autores principales: | Hu, Yaling, Jiang, Yingdi, Zhang, Zhenhao, Wang, Jingjing, Zhang, Bo, Gong, Lingli, Ji, Li, Pu, Zhening, Yang, Xusheng, Zou, Jian, Yin, Ying |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for Cancer Research
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9398152/ https://www.ncbi.nlm.nih.gov/pubmed/34610959 http://dx.doi.org/10.1158/1541-7786.MCR-20-1068 |
Ejemplares similares
-
Hierarchical Phosphorylation of HOXB13 by mTOR Dictates Its Activity and Oncogenic Function in Prostate Cancer
por: Chen, Yonghong, et al.
Publicado: (2023) -
TRAF4 Inhibits Bladder Cancer Progression by Promoting BMP/SMAD Signaling
por: Iyengar, Prasanna Vasudevan, et al.
Publicado: (2022) -
Identification of Autophagy-Related Genes as Targets for Senescence Induction Using a Customizable CRISPR-Based Suicide Switch Screen
por: Schepers, Arnout, et al.
Publicado: (2021) -
ATE1 Inhibits Liver Cancer Progression through RGS5-Mediated Suppression of Wnt/β-Catenin Signaling
por: Xu, Cong, et al.
Publicado: (2021) -
Dependence on the MUC1-C Oncoprotein in Classic, Variant, and Non–neuroendocrine Small Cell Lung Cancer
por: Fushimi, Atsushi, et al.
Publicado: (2022)