Mutations in Noncoding Cis-Regulatory Elements Reveal Cancer Driver Cistromes in Luminal Breast Cancer

Whole-genome sequencing of primary breast tumors enabled the identification of cancer driver genes and noncoding cancer driver plexuses from somatic mutations. However, differentiating driver from passenger events among noncoding genetic variants remains a challenge. Herein, we reveal cancer-driver...

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Detalles Bibliográficos
Autores principales: El Ghamrasni, Samah, Quevedo, Rene, Hawley, James, Mazrooei, Parisa, Hanna, Youstina, Cirlan, Iulia, Zhu, Helen, Bruce, Jeff P., Oldfield, Leslie E., Yang, S.Y. Cindy, Guilhamon, Paul, Reimand, Jüri, Cescon, Dave W., Done, Susan J., Lupien, Mathieu, Pugh, Trevor J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2022
Materias:
Cancer “-Omics”
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9398156/
https://www.ncbi.nlm.nih.gov/pubmed/34556523
http://dx.doi.org/10.1158/1541-7786.MCR-21-0471

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9398156/
https://www.ncbi.nlm.nih.gov/pubmed/34556523
http://dx.doi.org/10.1158/1541-7786.MCR-21-0471

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