Cargando…

Mutations in Noncoding Cis-Regulatory Elements Reveal Cancer Driver Cistromes in Luminal Breast Cancer

Whole-genome sequencing of primary breast tumors enabled the identification of cancer driver genes and noncoding cancer driver plexuses from somatic mutations. However, differentiating driver from passenger events among noncoding genetic variants remains a challenge. Herein, we reveal cancer-driver...

Descripción completa

Detalles Bibliográficos
Autores principales:	El Ghamrasni, Samah, Quevedo, Rene, Hawley, James, Mazrooei, Parisa, Hanna, Youstina, Cirlan, Iulia, Zhu, Helen, Bruce, Jeff P., Oldfield, Leslie E., Yang, S.Y. Cindy, Guilhamon, Paul, Reimand, Jüri, Cescon, Dave W., Done, Susan J., Lupien, Mathieu, Pugh, Trevor J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for Cancer Research 2022
Materias:	Cancer “-Omics”
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9398156/ https://www.ncbi.nlm.nih.gov/pubmed/34556523 http://dx.doi.org/10.1158/1541-7786.MCR-21-0471

Ejemplares similares

A Metabolomics Approach to Screening for Autism Risk in the Children's Autism Metabolome Project
por: Smith, Alan M., et al.
Publicado: (2020)

The AutGO Initiative: A Conceptual Framework for Developing Genetics‐Outcomes Research Hypotheses
por: Talebizadeh, Zohreh, et al.
Publicado: (2020)

The composition and turnover of the Arabidopsis thaliana 80S cytosolic ribosome
por: Salih, Karzan Jalal, et al.
Publicado: (2020)

Multi-omic analysis reveals HIP-55-dependent regulation of cytokines release
por: Jiang, Yunqi, et al.
Publicado: (2020)

Temporal modulation of the NF-κB RelA network in response to different types of DNA damage
por: Campbell, Amy E., et al.
Publicado: (2021)

Expression Changes in Epigenetic Gene Pathways Associated With One‐Carbon Nutritional Metabolites in Maternal Blood From Pregnancies Resulting in Autism and Non‐Typical Neurodevelopment
por: Zhu, Yihui, et al.
Publicado: (2020)

Lipidomic alteration of plasma in cured COVID-19 patients using ultra high-performance liquid chromatography with high-resolution mass spectrometry
por: Bai, Yunpeng, et al.
Publicado: (2021)

Serum biomarker discovery related to pathogenesis in acute coronary syndrome by proteomic approach
por: Shin, Miji, et al.
Publicado: (2021)

OMIC-05. PHOSPHOPROTEOMIC ANALYSIS IDENTIFIES SUBGROUP ENRICHED PATHWAYS AND KINASE SIGNATURES IN MEDULLOBLASTOMA
por: Leskoske, Kristin, et al.
Publicado: (2021)

OMIC-06. MOLECULAR SUBGROUPING OF MEDULLOBLASTOMA VIA LOW-DEPTH WHOLE GENOME BISULFITE SEQUENCING
por: Thompson, Dean, et al.
Publicado: (2021)

OMIC-02. COGNITIVE DEFICITS AND ALTERED FUNCTIONAL BRAIN NETWORK ORGANIZATION IN PEDIATRIC BRAIN TUMOR PATIENTS
por: Seitzman, Benjamin, et al.
Publicado: (2021)

OMIC-08. COMPOUND HETEROZYGOSITY OF POLE AND PMS2 LEADS TO CMMRD-LIKE PHENOTYPE- “POLYNCH” SYNDROME
por: Michaeli, Orli, et al.
Publicado: (2021)

OMIC-14. OPENPBTA: AN OPEN PEDIATRIC BRAIN TUMOR ATLAS
por: Shapiro, Joshua, et al.
Publicado: (2021)

OMIC-12. PREVALENCE AND SPECTRUM OF GERMLINE PATHOGENIC VARIANTS IN CANCER PREDISPOSITION GENES ACROSS THE CHILDREN’S BRAIN TUMOR NETWORK (CBTN)
por: Vaksman, Zalman, et al.
Publicado: (2021)

OMIC-13. THE ROLE OF COPY NUMBER ALTERATIONS IN PREDICTING SURVIVAL AND INFLUENCING TREATMENT OF CHILDHOOD BRAIN TUMORS
por: Freshour, Sharon, et al.
Publicado: (2021)

OMIC-04. IDENTIFICATION AND CHARACTERIZATION OF CIRCULATING RNAS (CODING AND NONCODING) AND METABOLITES IN CEREBROSPINAL FLUID IN MEDULLOBLASTOMA PATIENTS
por: Lee, Bongyong, et al.
Publicado: (2021)

OMIC-10. TRANSCRIPTOMIC ANALYSIS REVEALS SEX DIFFERENCES IN PEDIATRIC BRAIN MECHANISMS
por: Yang, Wei, et al.
Publicado: (2021)

OMIC-11. SINGLE CELL RNA SEQUENCING FROM THE CSF OF SUBJECTS WITH H3K27M+ DIPG/DMG TREATED WITH GD2 CAR T-CELLULAR THERAPY
por: Mochizuki, Aaron, et al.
Publicado: (2021)

OMIC-03. TRANSLATIONAL CONTROL IN MYC AND MYCN MEDULLOBLASTOMA
por: Schmidt, Christin, et al.
Publicado: (2021)

OMIC-07. FEASIBILITY AND UTILITY OF EPIGENOMIC PROFILING FOR CHILDHOOD CNS TUMORS IN HONG KONG
por: P.Y. Liu, Anthony, et al.
Publicado: (2021)

OMIC-09. MAPPING THE HISTONE MUTATIONAL LANDSCAPE ACROSS ADULT AND PEDIATRIC CANCER GENOMES UNCOVERS NOVEL SOMATIC MUTATIONS IN PEDIATRIC HIGH-GRADE GLIOMAS
por: Bonner, Erin, et al.
Publicado: (2021)

OMIC-01. THE LANDSCAPE OF EXTRACHROMOSOMAL CIRCULAR DNA IN MEDULLOBLASTOMA SUBGROUPS
por: Chapman, Owen, et al.
Publicado: (2021)

The ALA5/ALA6/ALA7 repeat polymorphisms of the glutathione peroxidase‐1 ( GPx1 ) gene and autism spectrum disorder
por: Carducci, Federica, et al.
Publicado: (2022)

LRFN5 locus structure is associated with autism and influenced by the sex of the individual and locus conversions
por: Lybæk, Helle, et al.
Publicado: (2022)

Assessing the utility of electronic measures as a proxy for cognitive ability
por: Levy, Tess, et al.
Publicado: (2022)

Surface-sampling mass spectrometry to study proteins and protein complexes
por: Wong, Kei F. Carver, et al.
Publicado: (2023)

Unlocking the secrets of the microbiome: exploring the dynamic microbial interplay with humans through metabolomics and their manipulation for synthetic biology applications
por: Muhamadali, Howbeer, et al.
Publicado: (2023)

Comparative transcriptomic analysis reveals the underlying molecular mechanism in high-fat diet-induced islet dysfunction
por: Wan, Shengrong, et al.
Publicado: (2023)

Identifying clusters of cis-regulatory elements underpinning TAD structures and lineage-specific regulatory networks
por: Madani Tonekaboni, Seyed Ali, et al.
Publicado: (2019)

Genome-wide cis-decoding for expression design in tomato using cistrome data and explainable deep learning
por: Akagi, Takashi, et al.
Publicado: (2022)

A Functional Precision Oncology Approach to Identify Treatment Strategies for Myxofibrosarcoma Patients
por: Pauli, Chantal, et al.
Publicado: (2022)

MUC1-C Dictates JUN and BAF-Mediated Chromatin Remodeling at Enhancer Signatures in Cancer Stem Cells
por: Bhattacharya, Atrayee, et al.
Publicado: (2022)

DNA Methylation and gene expression patterns are widely altered in fetal growth restriction and associated with FGR development
por: Lee, Seoyeong, et al.
Publicado: (2021)

Regulation of Chemosensitivity in Human Medulloblastoma Cells by p53 and the PI3 Kinase Signaling Pathway
por: Naeem, Aisha, et al.
Publicado: (2022)

Comprehensive analysis of the prognostic value and immune implications of the TTK gene in lung adenocarcinoma: a meta-analysis and bioinformatics analysis
por: Li, Bo, et al.
Publicado: (2022)

Longitudinal Analysis of Human Pancreatic Adenocarcinoma Development Reveals Transient Gene Expression Signatures
por: Kim, Jungsun, et al.
Publicado: (2021)

Human Papillomavirus Integration Strictly Correlates with Global Genome Instability in Head and Neck Cancer
por: Labarge, Brandon, et al.
Publicado: (2022)

Origins and Timing of Emerging Lesions in Advanced Renal Cell Carcinoma
por: Wallace, Andrew, et al.
Publicado: (2022)

The Role of ARID1A in the Nonestrogenic Modulation of IGF-1 Signaling
por: Jdeed, Sham, et al.
Publicado: (2022)

Branching Copy-Number Evolution and Parallel Immune Profiles across the Regional Tumor Space of Resected Pancreatic Cancer
por: Petersson, Alexandra, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_4i9dv4p0rv4d9ccukpsab3qn8l