Vimseltinib: A Precision CSF1R Therapy for Tenosynovial Giant Cell Tumors and Diseases Promoted by Macrophages

Macrophages can be co-opted to contribute to neoplastic, neurologic, and inflammatory diseases. Colony-stimulating factor 1 receptor (CSF1R)-dependent macrophages and other inflammatory cells can suppress the adaptive immune system in cancer and contribute to angiogenesis, tumor growth, and metastas...

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Detalles Bibliográficos
Autores principales: Smith, Bryan D., Kaufman, Michael D., Wise, Scott C., Ahn, Yu Mi, Caldwell, Timothy M., Leary, Cynthia B., Lu, Wei-Ping, Tan, Gege, Vogeti, Lakshminarayana, Vogeti, Subha, Wilky, Breelyn A., Davis, Lara E., Sharma, Maitreyi, Ruiz-Soto, Rodrigo, Flynn, Daniel L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2021
Materias:
MCT First Disclosures
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9398179/
https://www.ncbi.nlm.nih.gov/pubmed/34433663
http://dx.doi.org/10.1158/1535-7163.MCT-21-0361

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9398179/
https://www.ncbi.nlm.nih.gov/pubmed/34433663
http://dx.doi.org/10.1158/1535-7163.MCT-21-0361

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