Superoxide dismutase 2 ameliorates mitochondrial dysfunction in skin fibroblasts of Leber’s hereditary optic neuropathy patients

BACKGROUND: In Leber’s hereditary optic neuropathy (LHON), mtDNA mutations mediate mitochondrial dysfunction and apoptosis of retinal ganglion cells. Mitochondrial superoxide dismutase 2 (SOD2) is a crucial antioxidase against reactive oxygen species (ROS). This study aims to investigate whether SOD...

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Detalles Bibliográficos
Autores principales: Zhou, Qingru, Yao, Shun, Yang, Mingzhu, Guo, Qingge, Li, Ya, Li, Lei, Lei, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9398213/
https://www.ncbi.nlm.nih.gov/pubmed/36017189
http://dx.doi.org/10.3389/fnins.2022.917348

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9398213/
https://www.ncbi.nlm.nih.gov/pubmed/36017189
http://dx.doi.org/10.3389/fnins.2022.917348

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