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Self-organization of kinetochore-fibers in human mitotic spindles

During eukaryotic cell division, chromosomes are linked to microtubules (MTs) in the spindle by a macromolecular complex called the kinetochore. The bound kinetochore microtubules (KMTs) are crucial to ensuring accurate chromosome segregation. Recent reconstructions by electron tomography (Kiewisz e...

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Detalles Bibliográficos
Autores principales: Conway, William, Kiewisz, Robert, Fabig, Gunar, Kelleher, Colm P, Wu, Hai-Yin, Anjur-Dietrich, Maya, Müller-Reichert, Thomas, Needleman, Daniel J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9398449/
https://www.ncbi.nlm.nih.gov/pubmed/35876665
http://dx.doi.org/10.7554/eLife.75458