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Trophectoderm differentiation to invasive syncytiotrophoblast is promoted by endometrial epithelial cells during human embryo implantation

STUDY QUESTION: How does the human embryo breach the endometrial epithelium at implantation? SUMMARY ANSWER: Embryo attachment to the endometrial epithelium promotes the formation of multinuclear syncytiotrophoblast from trophectoderm, which goes on to breach the epithelial layer. WHAT IS KNOWN ALRE...

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Detalles Bibliográficos
Autores principales: Ruane, Peter T, Garner, Terence, Parsons, Lydia, Babbington, Phoebe A, Wangsaputra, Ivan, Kimber, Susan J, Stevens, Adam, Westwood, Melissa, Brison, Daniel R, Aplin, John D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9398450/
https://www.ncbi.nlm.nih.gov/pubmed/35079788
http://dx.doi.org/10.1093/humrep/deac008