Reengineering of 7-dehydrocholesterol biosynthesis in Saccharomyces cerevisiae using combined pathway and organelle strategies

7-Dehydrocholesterol (7-DHC) is a widely used sterol and a precursor of several costly steroidal drugs. In this study, 7-DHC biosynthesis pathway was constructed and modified in Saccharomyces cerevisiae. Firstly, the biosynthesis pathway was constructed by knocking out the competitive pathway genes...

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Detalles Bibliográficos
Autores principales: Wei, Wenqian, Gao, Song, Yi, Qiong, Liu, Anjian, Yu, Shiqin, Zhou, Jingwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9398459/
https://www.ncbi.nlm.nih.gov/pubmed/36016783
http://dx.doi.org/10.3389/fmicb.2022.978074

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9398459/
https://www.ncbi.nlm.nih.gov/pubmed/36016783
http://dx.doi.org/10.3389/fmicb.2022.978074

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