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Suprachoroidal Injection of Triamcinolone Acetonide Suspension: Ocular Pharmacokinetics and Distribution in Rabbits Demonstrates High and Durable Levels in the Chorioretina

PURPOSE: To compare ocular pharmacokinetics (PK), systemic absorption, and injectability of triamcinolone acetonide (TA) suprachoroidal (SC) and intravitreal (IVT) suspensions. METHODS: New Zealand White (NZW) rabbits received a bilateral injection of 4 mg TA injectable suspension, TRI (TRIESENCE (®...

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Detalles Bibliográficos
Autores principales: Muya, Leroy, Kansara, Viral, Cavet, Megan E., Ciulla, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9398478/
https://www.ncbi.nlm.nih.gov/pubmed/35404132
http://dx.doi.org/10.1089/jop.2021.0090