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Spatial organization and early signaling of the B-cell receptor in CLL

Most chronic lymphocytic leukemia (CLL) clones express B-cell receptors (BcR) of both IgM/IgD isotypes; however, 5%–10% of CLL cases express isotype-switched immunoglobulin G (IgG). The early signaling and spatial patterning of the various BcRs at steady state and after activation are still fully un...

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Detalles Bibliográficos
Autores principales: Shorer Arbel, Yamit, Bronstein, Yotam, Dadosh, Tali, Kamdjou, Talia, Tsuriel, Shlomo, Shapiro, Mika, Katz, Ben-Zion, Herishanu, Yair
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9398492/
https://www.ncbi.nlm.nih.gov/pubmed/36016925
http://dx.doi.org/10.3389/fimmu.2022.953660