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HIF-1α Ameliorates Diabetic Neuropathic Pain via Parkin-Mediated Mitophagy in a Mouse Model

Mitochondrial dysfunction, which can be regulated by mitophagy, plays a central role in diabetic neuropathic pain (DNP). Mitophagy that was involved in nerve damage-induced neuropathic pain has been reported. Hyperglycemia and cellular hypoxic were the two main characters of diabetes. Hypoxia-induci...

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Detalles Bibliográficos
Autores principales: He, Jian, Qin, Zaisheng, Chen, Xin, He, Wanyou, Li, Donglin, Zhang, Lei, Le, Yue, Xiong, Qingming, Zhang, Bin, Wang, Hanbing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9398773/
https://www.ncbi.nlm.nih.gov/pubmed/36017378
http://dx.doi.org/10.1155/2022/5274375