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PFKFB3 Increases IL-1β and TNF-α in Intestinal Epithelial Cells to Promote Tumorigenesis in Colitis-Associated Colorectal Cancer

Colorectal cancer (CRC) is significantly correlated with inflammatory bowel disease, which usually manifests as chronic relapsing-remitting colitis. Phosphofructo-2-kinase/fructose-2,6-biophosphatase 3 (PFKFB3) can catalyze to produce fructose-2,6-bisphosphate and function as an oncogene. In this st...

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Detalles Bibliográficos
Autores principales: Yu, Hongbin, Dai, Chuang, Zhu, Wei, Jin, Yude, Wang, Chunhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9398832/
https://www.ncbi.nlm.nih.gov/pubmed/36016583
http://dx.doi.org/10.1155/2022/6367437