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Inhibition of TNF-α and JNK Signaling Pathway Can Reduce Paclitaxel-Induced Apoptosis of Mouse Cardiomyocytes

Paclitaxel (PTX) is a widely used chemotherapeutic drug for treating tumors. However, studies have shown that it can cause cardiac problems such as arrhythmia, myocarditis, chronic cardiomyopathy, and heart failure. Therefore, it is essential to study the mechanism behind the cardiotoxicity of PTX i...

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Detalles Bibliográficos
Autores principales: Ren, Shuang, Huang, Tianwen, Ou, Danyan, Feng, Luhuai, Huang, Sisi, Zhou, Chaonan, Ge, Lianying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9398847/
https://www.ncbi.nlm.nih.gov/pubmed/36016921
http://dx.doi.org/10.1155/2022/8460121