Development of a novel pharmacophore model to screen specific inhibitors for the serine-threonine protein phosphatase calcineurin

Calcineurin (CaN) is a calcium/calmodulin-dependent serine/threonine phosphatase with a crucial role in cellular homeostasis. It is also the target of the Food and Drug Administration (FDA) approved immunosuppressant drugs FK506 and cyclosporine A. Recent work from our group and others indicated tha...

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Detalles Bibliográficos
Autores principales: Mukherjee, Abhisek, Cuanalo-Contreras, Karina, Sood, Abha, Soto, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9398911/
https://www.ncbi.nlm.nih.gov/pubmed/36032402
http://dx.doi.org/10.1016/j.bbrep.2022.101311

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9398911/
https://www.ncbi.nlm.nih.gov/pubmed/36032402
http://dx.doi.org/10.1016/j.bbrep.2022.101311

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